Your browser doesn't support javascript.
loading
Effects of rosiglitazone on the mRNA expressions of MMP-1、TIMP-1 and Collagen Ⅲ in rat kidney fibroblasts cultured in high glucose / 中国实用内科杂志
Chinese Journal of Practical Internal Medicine ; (12)2000.
Article in Chinese | WPRIM | ID: wpr-559146
ABSTRACT
Objective To investigate into the protective effects of rosiglitazone on rat kidney fibroblasts(NRK)damaged by high glucose.Methods From Jan.2005 to Sep.2005,the NRK cells were cultured in vitro,and were divided into five groupsnormal glucose group(NG,1 000 mg/L D-glucose),high glucose group(HG,4 500 mg/L D-glucose),HG+RGZ(5 ?mol/L),HG+RGZ(10 ?mol/L)and HG+RGZ(15 ?mol/L).The mRNA expressions of T MMP-1、TIMP-1 and Collagen Ⅲ were measured with RT-PCR.Results Compared with NG group,the mRNA expression of MMP-1 decreased markedly in HG group(P

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Practical Internal Medicine Year: 2000 Type: Article

Similar

MEDLINE

...
LILACS

LIS

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Practical Internal Medicine Year: 2000 Type: Article