Relationship between the lesion type and extent of calcified valvular heart disease and coronary heart disease / 解放军医学杂志

ABSTRACT

Objective To explore the incidence and predisposing factors of coronary heart disease (CHD) among the patients with different types and extent of calcified valvular heart disease (CVHD). Methods 574 patients with CVHD diagnosed by echocardiography were divided into mild and severe groups based on the hemodynamic changes. The differences of incidence and predisposing factors of coronary heart disease between the two groups were compared. Results Ninety-seven cases of CVHD were categorized as having severe lesion, including aortic stenosis subgroup (AS group), aortic insufficiency subgroup (AI group) and mitral valve subgroup (MV group). All other patients were having mild lesions. There was no significant difference in blood pressure, blood lipid, fasting blood glucose, age and incidence of CAD, incidences in hypertension, hyperlipidemia and diabetes mellitus between two groups. Conclusions Mild CVHD showed similar prognostic value as that of severe CVHD, therefore it should not be ignored.