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Effect of rosiglitazone on insulin sensitivity and ?-cell function in polycystic ovary syndrome patients with insulin resistance / 第三军医大学学报
Journal of Third Military Medical University ; (24)2003.
Article in Chinese | WPRIM | ID: wpr-560015
ABSTRACT
Objective To explore the effect of rosiglitazone on the insulin sensitivity and ?-cell function in polycystic ovary syndrome(PCOS)patients accompanied with insulin resistance.Methods Rosiglitazone was given to 15 patients PCOS with insulin resistance at a dose of 4 mg daily for 12 weeks.All patients underwent an oral glucose tolerance test and Botnia clamp,and their body mass index(BMI),waist/hip ratio(WHR),serum pressure,follicle-stimulating hormone(FSH),luteinizing hormone(LH),testosterone,free testosterone(FT),glucose and insulin were determined and compared before and at the end of the treatment.Results After 12 weeks' treatment,Waist/Hip ratio,FT and LH/FSH ratio,and fasting insulin were significantly decreased(P

Full text: Available Index: WPRIM (Western Pacific) Type of study: Diagnostic study Language: Chinese Journal: Journal of Third Military Medical University Year: 2003 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Type of study: Diagnostic study Language: Chinese Journal: Journal of Third Military Medical University Year: 2003 Type: Article