Clinicopathologic characteristics of myocardial infarction with or without cardiac rupture in the gerontal patients / 解放军医学杂志

ABSTRACT

Objective To investigate different clinicopathologic changes in myocardial infarction with and without cardiac rupture in the gerontal patients. Methods 107 gerontal patients with myocardial infarction (rupture group 22, non-rupture group 85) confirmed by necropsy during Jan. 1980 to Oct. 2003 were analyzed to compare the clinicopathologic findings between patients with cardiac rupture and without rupture. Results The mean age of rupture group was higher than that of non-rupture (79.1?9.1 vs 71.8?10.9 years old, P=0.0059). The number of female patients (50.0% vs 24.6%, P=0.0209) and the the number of patients suffering from myocardial infarction for the first time (57.3% vs 52.3%, P=0.0312) were both greater in the rupture group. Previous angina pectoris was significantly less frequently found in the rupture group compared with non-rupture group (45.5% vs 87.1%, P=0.0000). The mean number of major coronary arteries with over 75% stenosis was significantly lower in the rupture group (1.64 vs 2.28 branches/person, P=0.0068). The percentage of single major coronary arteries with significant stenosis was more often seen in the rupture group (59.1% vs 33.8%, P=0.0325). The site of cardiac rupture was more frequenfly located in anterior wall near the apex. Conclusion The results suggested that cardiac rupture occurred more often in older and female patients, in first myocardial infarction episode, with infrequent previous angina pectoris, and frequently involving a severe single coronary artery disease compared with those patients without cardiac rupture. The common location of rupture was anterior wall near the apex.