Alterations of intermedin and its receptor system in oleic acid-induced acute lung injury of rats / 北京大学学报(医学版)
Journal of Peking University(Health Sciences)
;
(6)2003.
Article
in Chinese
| WPRIM
| ID: wpr-560142
ABSTRACT
Objective:
To investigate the changes of pulmonary IMD and its receptor system - calcitonin receptor-like receptor (CL) and receptor activity modifying proteins (RAMPs) mRNA in acute lung injury(ALI) induced by oleic acid of rats.Methods:
Contents of IMD in plasma and lung homogenates were measured by radioimmunoassay(RIA). The lung mRNA of IMD, CL and RAMPs was determined by semi-quantitative RT-PCR.Results:
Compared with control group, in ALI group, the contents of IMD_ 1-53 in plasma and lung homogenates were decreased by 20.8% and 74.5% (all P
Full text:
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Peking University(Health Sciences)
Year:
2003
Type:
Article
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