The estrogen progesterone receptor,neu oncoprotein and be able to bear or endure of medicine and examine in the carcinoma of breast give voice to and significance / 中国基层医药

ABSTRACT

Objective To discuss estrogen receptor(ER),progesterone receptor(PR),neu oncoprotein(HER-2),P-glycoprotein(P-gp) and glatathione S-transferase pi(GST-?) in the carcinoma of breast give voice to and clinical significance.Methods The expressions of estrogen receptor,progesterone receptor,neu oncoprotein,P-glycoprotein and glatathione S-transferase pi manifold medicine were determined by immunity histochemistry technology in 85 cases of breast carcinoma.Results The 85 cases estrogen receptor masculine quotiety became 52%,progesterone receptor masculine quotiety became 51%,neu oncoprotein shadow quotiety became 54%,P-glycoprotein examine became (-)～(+) 85% and glatathione S-transferase pi examine became (-)～(+) 69% give voice to of masculine sign in the carcinoma of breast and clinical warfare had pertinence.Conclusion The estrogen receptor,progesterone receptor,neu oncoprotein,P-glycoprotein and glatathione S-transferase pi unite give voice to and of the carcinoma of breast warfare osculation pertinence.Jerque ER,PR,HER-2,P-gp and GST-? have important significance in instituting chems program of breast carcinoma.