Detection of Neuron-specific Enolase and Soluble Intercellar Adhesion Molecule-1 in Serum and Cerebrospinal Fluid in the Patients with Viral Encephalitis / 医学研究杂志
Journal of Medical Research
; (12)2006.
Article
in Zh
| WPRIM
| ID: wpr-560713
Responsible library:
WPRO
ABSTRACT
Objective To investigate the changes of the neuron-specific enolase(NSE) and soluble intercellar adhesion molecule-1(CAM-1) in serum and cerebrospinal fluid(CSF) in the patients with viral encephhalites (VE). Methods The levels of NSE and sICAM-1 in serum and CSF were determined before and after treatment using ELISA in 58 patients with VE and 20 normal persons. Results The levels of NSE and sICAM-1 in serum before treatment were obviously higher than those of control group, and their differences were significant (P0.05). Conclusions NSE and sICAM-1 may contribute to pathologic course in infection of VE and the levels of NSE and sICAM-1 in serum and CSF may serve as markers of differential diagnosis and clinical significance.
Full text:
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Index:
WPRIM
Type of study:
Diagnostic_studies
Language:
Zh
Journal:
Journal of Medical Research
Year:
2006
Type:
Article