Research into the standard process of fresh freeze - dried plasma for providing medical treatments with dutch dryer LY3-TTE/DM8
Journal of Medical Research
;
: 65-68, 2007.
Article
in Vietnamese
| WPRIM
| ID: wpr-561
ABSTRACT
Background:
Freeze - Dried Plasma (FDP) has many advantages, which could be stored for a long \ufffd?term and transported across remote areas for providing medical treatments and emergency aid.Objectives:
To study the standard process of freeze - dried fresh plasma. Subjects andmethods:
10 samples of fresh plasma from volunteer donors were selected according to certain categories. Plasma samples were frozen at \ufffd?75oC in 12 hours, freeze - dried at - 45oC and at the atmospheric pressure of 0.04mbar with Dutch dryer Ly - TTE/DM8. The adequate freeze - drying time for every 100ml of plasma was 60 hours. The protein level, factor VIII, electrolysis, the pH of plasma before and after the drying process were evaluated.Results:
Results of tracking protein level in comparison between before and after freeze - dry showed the components and levels of freeze-dried protein changed little, with no statistical significance (P>0.05). The clotting factor before and after freeze-dried retains standard activity. After the freeze-dried process, factor VIII achieved 0.80 Ul/ml, prothombin achieved >80%. However, prothrombin decreased clearly (P<0.05). Electrolytes and pH changed had no statistical significance (P> 0.05).Conclusions:
The procedures are applicable for processing and manufacturing drying plasma for long-term-storage and medical treatment. \r\n', u'\r\n', u'\r\n', u'
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Plasma
Language:
Vietnamese
Journal:
Journal of Medical Research
Year:
2007
Type:
Article
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