A retrospective study of single frozen-thawed blastocyst transfer / 대한생식의학회지
Clinical and Experimental Reproductive Medicine
;
: 106-111, 2016.
Article
in English
| WPRIM
| ID: wpr-56130
ABSTRACT
OBJECTIVE:
To study the clinical outcomes of single frozen-thawed blastocyst transfer cycles according to the hatching status of frozen-thawed blastocysts.METHODS:
Frozen-thawed blastocysts were divided into three groups according to their hatching status as follows less-than-expanded blastocyst (≤EdB), hatching blastocyst (HgB), and hatched blastocyst (HdB). The female age and infertility factors of each group were evaluated. The quality of the single frozen-thawed blastocyst was also graded as grade A, tightly packed inner cell mass (ICM) and many cells organized in the trophectoderm epithelium (TE); grade B, several and loose ICM and TE; and grade C, very few ICM and a few cells in the TE. The clinical pregnancy and implantation rate were compared between each group. The data were analyzed by either t-test or chi-square analysis.RESULTS:
There were no statistically significant differences in average female ages, infertility factors, or the distribution of blastocyst grades A, B, and C in each group. There was no significant difference in the clinical pregnancy and implantation rate of each group according to their blastocyst grade. However, there was a significant difference in the clinical pregnancy and implantation rate between each group. In the HdB group, the clinical pregnancy and implantation rate were similar regardless of the blastocyst quality.CONCLUSION:
There was an effect on the clinical outcomes depending on whether the blastocyst hatched during single frozen-thawed blastocyst transfer. When performing single frozen-thawed blastocyst transfer, the hatching status of the frozen-thawed blastocyst may be a more important parameter for clinical outcomes than the quality of the frozen-thawed blastocyst.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Blastocyst
/
Retrospective Studies
/
Embryo Transfer
/
Epithelium
/
Single Embryo Transfer
/
Vitrification
/
Infertility
Type of study:
Observational study
Limits:
Female
/
Humans
/
Pregnancy
Language:
English
Journal:
Clinical and Experimental Reproductive Medicine
Year:
2016
Type:
Article
Similar
MEDLINE
...
LILACS
LIS