Effect of Ambroxol on NF-?B activation of macrophage in the induced sputum in chronic obstructive pulmonary disease / 中国实用内科杂志
Chinese Journal of Practical Internal Medicine
;
(12)2002.
Article
in Chinese
| WPRIM
| ID: wpr-561303
ABSTRACT
Objective To investigate the effect of Ambroxol on NF?B activation of macrophage in the induced sputum in patients with stable COPD.Methods Induced sputum was taken from 47 stable COPD patients,who were divided into two groups randomly.Macrophages were collected,and NF-?B activation and IL-8 of induced sputum were determined by immunohistochemistry;SOD and MDA were determined synchronously.Results NF-?B activation in macrophage and IL-8 in the treated group were significantly decreased in patients of stable group than those in the controls.Conclusion Ambroxol can decrease NF-?B activation in macrophage in stable COPD patients.
Full text:
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Practical Internal Medicine
Year:
2002
Type:
Article
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