Application of total parenteral nutrition with alanyl-glutamine dipeptide in postoperative patients of gastrointestinal neoplasms / 第三军医大学学报

ABSTRACT

Objective To investigate the application of total parenteral nutrition with alanyl-glutamine dipeptide in postoperative patients of gastrointestinal neoplasms.Methods Sixty-four postoperative patients of gastrointestinal neoplasms were randomly divided into study group and control group.The patients in the two groups all received isocaloric(96.0 kJ?kg-1?d-1)and isonitrogen(0.25 g?kg-1?d-1)parenteral nutrition from postoperative day 1 to day 7,and the study group received additional alanyl-glutamine.The serum levels of albumin,pre-albumin,IgG,IgA,IgM,C3,C4 were measured before operation and on postoperative day 1 and 8.Nitrogen balance was calculated on postoperative day 1,4 and 8.Results Compared with preoperation,the serum levels of albumin and pre-albumin were both significantly decreased in two groups(P