Detection and Analysis of Nitric Oxide Level in Gingival Tissue in Experimental Animal Model of Periodontitis / 医学研究杂志

ABSTRACT

Objective To investigate the role of nitric oxide(NO)in the pathogenesis of periodontal diseases by detecting and analyzing NO level in gingival tissue in experimental animal model of periodontitis.Methods Experimental animal model of periodontitis in rats was built.Then NO2-and NO3-concentrations,which reflect NO level indirectly,were measured by NO kit in gingival tissue of rat with experimental periodontitis.Results The significant differences of NO level in gingival tissue were found among normal group,gingivitis group and periodontitis group(P