Study of the relationship between plasma homocysteine thiolactone concentrations and type 2 diabetic macrovascular complications / 中国实用内科杂志
Chinese Journal of Practical Internal Medicine
;
(12)2006.
Article
in Chinese
| WPRIM
| ID: wpr-562067
ABSTRACT
Objective To investigate the role of homocysteine(Hcy)and homocysteine thiolactone(HcyT)in the development of macrovascular complications in patients with type 2 DM.Methods A total of 160 subjects were recruited in this study40 healthy controls,120 with type 2 DM.Plasma Hcy levels were measured by Polarization Immunoassay(FPIA),and HcyT concentrations were monitored using high-performance liquid chromatography(HPLC)on a reversephase C18 column with ultraviolet detection.Plasma folic acid and Vitamin B12 levels were measured with radioimmunoassay method.Results Plasma Hcy and HcyT concentrations in type 2 DM patients were significantly higher than healthy controls[Hcy9.28(7.51~11.82)?mol/L vs 5.64(5.17~8.00)?mol/L,P
Full text:
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Practical Internal Medicine
Year:
2006
Type:
Article
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