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Effect of Itraconazole/IFN-gamma on IFN-gamma and IL-10 in Nude Mice and Mice / 医学研究杂志
Journal of Medical Research ; (12)2006.
Article in Chinese | WPRIM | ID: wpr-562117
ABSTRACT
Objective To study the effect of itraconazole/IFN-gamma on IFN-? and IL-10 in nude mice and mice and clinical significance. Methods Systemic infection of animals that induced by abdominal injection of Candida albicans and Cryptococcus neoformans, Expression of IFN-? and IL-10 were detected by enzyme-linked immunosorbent assay (ELISA).Results After treated with Itraconazole and IFN-gamma, the levels of IFN-gamma were increased and ones of IL-10 were decreased significantly. Conclusions Itraconazole and IFN-gamma may play key roles in the immune function of those animals.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Journal of Medical Research Year: 2006 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Journal of Medical Research Year: 2006 Type: Article