Vitamin E Succinate inhibits growth and induces apoptosis of prostate cancer cell line PC-3 / 第二军医大学学报
Academic Journal of Second Military Medical University
;
(12)2001.
Article
in Chinese
| WPRIM
| ID: wpr-562159
ABSTRACT
Objective:
To study the inhibitory and apoptosisinducing effect of vitamin E succinate(VES) on androgen-independent prostate cancer cell line PC-3 in vitro.Methods:
VES was dissolved with ethanol to obtain VES solution.PC-3 cells of logarithmic growth phase were treated with various concentrations of VES solution(25,50,75,100,and 125mg/L);cells in control group were treated with 1.25% ethanol.MTT method was used to measure the viability and inhibitory rate of cells in each group 24h,48h and 72h after VES treatment;flow cytometry was employed to determine the apoptosis rate of the PC-3 cells.Results:
The viability of cells in the experimental groups was significantly lower than that in the control group(P
Full text:
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Academic Journal of Second Military Medical University
Year:
2001
Type:
Article
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