Alpha competitive structure in children with attention deficit hyperactivity disorder with/without learning disabilities / 北京大学学报(医学版)

ABSTRACT

Objective:To explore the alpha competitive structure in children with attention deficit hyperactivity disorder(ADHD)with/without learning disabilities(LD).Methods:According to DSM-Ⅳ diagnostic criteria,the study involved ADHD children with LD,pure ADHD children and normal controls.Each group consisted of 68 subjects.All subjects were between the ages of 7 and 14 years,and the groups were matched by sex,age and ADHD subtypes.EEG data were recorded during an eye-closed resting period and then were analyzed with EEG-encephaloflutuographic technology(EEG-ET).Results:(1)The pure ADHD children showed significantly more 8 Hz activity(25.84%?14.81%)than that of the normal control group(16.50%?11.42%,P=0.000);The main frequency of alpha band was 10 Hz in the pure ADHD children,while the energy distribution among alpha components was diffuse.(2)ADHD children with LD showed significantly more 8 Hz and 13 Hz activity(25.11%?11.88%,1.14%?1.14%,separately)than that of the normal control(16.50%?11.42%,0.74%?0.97%,P=0.000,P=0.009,separately);The dominant probability of 10 Hz(27.80%?13.28%)in this group was significantly lower than that of the control group(36.06%?17.21%,P=0.011);The energy distribution among alpha components was diffuse in ADHD children with LD,whose main frequency of alpha band was 9 Hz;The entropy value of the ADHD children with LD was significantly higher than that of the control group in the right brain and the left parietal region,temporal region,occipital region(P