High-frequency contrast-enhanced ultrasound in evaluating perfusion of superficial lesions:limitations and countermeasures / 第二军医大学学报

ABSTRACT

Objective:To evaluate the perfusion defect of superficial lesions by high-frequency contrast-enhanced ultrasound through comparing the results of low-frequency and high-frequency contrast-enhanced ultrasound,and to put forward the preliminary countermeasures.Methods:Twenty-three patients(9 male and 14 female,aged 45.87?9.32 years,ranging 34-73 years)with 6 sorts of superficial lesions,including 1 parotid pleomorphic adenoma,3 thyroid adenomas,5 thyroid adenocarcinomas,5 cervical metastases,7 breast carcinomas and 2 of testicular seminomas,were examined by both low-frequency and high-frequency contrast-enhanced ultrasounds.CEUS with SonoVue under CPS-Cadence mode was performed for each lesion using abdominal probe(low-frequency probe)5 min before small parts probe(high-frequency probe).ACQ software was used to determine the peak intensity(PI)and the results were analyzed by Student's t test in pairs.Results:The PI values of all the 6 types of lesions were significantly lower in high-frequency contrast-enhanced ultrasound images than those in the low-frequency contrast-enhanced ultrasound images(P