STUDY ON BIOAVAILABILITY AND TOXICITY OF SELENIUM FROM METHYLSELENOCYSTEINE / 营养学报
Acta Nutrimenta Sinica
; (6)2004.
Article
in Zh
| WPRIM
| ID: wpr-562645
Responsible library:
WPRO
ABSTRACT
Objective:With selenomethionine as reference,we investigated the bioavailability and toxicity of methylselenocysteine. Method:Selenium retention,glutathione peroxidase and thioredoxin reductase activities were tested to compare bioavailability. Acute toxicity and short-term selenium-tolerance were studied to compare toxicity. Results:Selenomethionine and methylselenocysteine were comparable in ability of increasing selenoenzymes. Selenomethionine caused much higher selenium retention,especially at higher levels and lower toxicity indicated by acute toxicity and short-term selenium-tolerance. Conclusion:Compared with selenomethionine,methylselenocysteine has equal efficacy on selenoenzymes with the characterization of less retention,but higher toxicity.
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WPRIM
Language:
Zh
Journal:
Acta Nutrimenta Sinica
Year:
2004
Type:
Article