STUDY ON BIOAVAILABILITY AND TOXICITY OF SELENIUM FROM METHYLSELENOCYSTEINE / 营养学报
Acta Nutrimenta Sinica
;
(6)2004.
Article
in Chinese
| WPRIM
| ID: wpr-562645
ABSTRACT
Objective:
With selenomethionine as reference,we investigated the bioavailability and toxicity of methylselenocysteine.Method:
Selenium retention,glutathione peroxidase and thioredoxin reductase activities were tested to compare bioavailability. Acute toxicity and short-term selenium-tolerance were studied to compare toxicity.Results:
Selenomethionine and methylselenocysteine were comparable in ability of increasing selenoenzymes. Selenomethionine caused much higher selenium retention,especially at higher levels and lower toxicity indicated by acute toxicity and short-term selenium-tolerance.Conclusion:
Compared with selenomethionine,methylselenocysteine has equal efficacy on selenoenzymes with the characterization of less retention,but higher toxicity.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Acta Nutrimenta Sinica
Year:
2004
Type:
Article
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