Effect of poly(ADP-ribose)polymerase inhibitor 5-AIQ on invasion and metastasis of CT26 cells / 第三军医大学学报
Journal of Third Military Medical University
;
(24)1983.
Article
in Chinese
| WPRIM
| ID: wpr-562998
ABSTRACT
Objective To study the effect of poly(ADP-ribose)polymerase(PARP)inhibitor 5-AIQ on the adhesion,migration and invasion of mouse colon adenocarcinoma cell line(CT26).Methods The expression of PARP after 5-AIQ treatment was detected Western blot.The cell adhesion,migration and invasion of CT26 after 5-AIQ treatment were observed by cell-matrix adhesion assay,cell migration assay and matrigel invasion assay.Results The expression of PARP in 5-AIQ-treated CT26 was weaker than that in 5-AIQ-untreated cells(P
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Third Military Medical University
Year:
1983
Type:
Article
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