Influence of ulinastain on tumor necrosis factor and interleukin-6 in patients after cardiopulmonary resuscitation / 中国实用内科杂志

ABSTRACT

Objective To investigate the incidence of systemic inflammatory response syndrome(SIRS)after cardiopulmonary resuscitation(CPR)and to observe the effect of ulinastain in inhibition of inflammatory mediator.Methods Thirty-two patients surviving more than 72 hours after CPR were divided into ulinastain group and control group randomly.Activity of TNF-? and IL-6 of these patients was detected.In the meantime,all patients were evaluated by SIRS diagnosis and all data were compared between two groups.Results Activities of TNF-? and IL-6 in patients after CPR were significantly higher than that of normal people(P