Effects of progesterone on amino acid neurotransmitters released from rat cerebral cortical neurons / 中国药理学通报
Chinese Pharmacological Bulletin
; (12)1986.
Article
in Zh
| WPRIM
| ID: wpr-563537
Responsible library:
WPRO
ABSTRACT
Aim To investigate the effect of progesterone on the levels of glutamate and ?-aminobutyric acid released from primary cultured rat cerebral cortical neurons.Methods Primary cultured rat cerebral cortical neurons were treated with PROG(10 ?mol?L-1) and the concentrations of amino acid in cell culture media at different time(0.5,1,1.5,2,24,36,48,72 h) were measured by OPA-mercaptoethanol precolumn derivatization technique and HPLC-FLD.Results Compared with control group,PROG treatment significantly reduced the levels of GLU at the time of 1,1.5,2,24,36,48,72 h(P
Full text:
1
Index:
WPRIM
Language:
Zh
Journal:
Chinese Pharmacological Bulletin
Year:
1986
Type:
Article