The relationships between Ultrasonographic Features and the Expression of estrogen receptor and progesterone receptor in Postmenopausal Women with Infiltrating Ductal Carcinoma of Breast / 解放军医学杂志

ABSTRACT

Objective To investigate the relationships between of 2-dimensional (2D) and color Doppler ultrasonographic features and the expressions of both estrogen receptor (ER) and progesterone receptor (PR) in postmenopausal women with infiltrating ductal carcinoma (IDC) in breast, and to evaluate the feasibility of predicting the expressions of ER and PR in IDC by means of ultrasonographic features. Methods The clinical data of 96 patients with breast infiltrating ductal carcinoma diagnosed by pathology during Jun. 2002 to Jun. 2007 were retrospectively analyzed. The correlation between ultrasonographic features and both ER and PR expressions in the mastectomy specimens determined by immunohistochemical technique was statistically analyzed. Results Of the 96 cases, the positive expression rates of ER and PR were 54.17% and 50%, respectively, the bi-positive and bi-negative expression rates of ER and PR were 41.67% and 37.5%, respectively. Among the breast carcinoma, the positive expression rate of ER was higher in tumor with ultrasonographic spicule sign (P