Expression of Human Vascular Endothelial Growth Factor 165 in Ischemically Damaged Bind Limb in a Rabbit Model with Transplantation of Mesenchymal Stem Cells / 医学研究杂志
Journal of Medical Research
;
(12)2006.
Article
in Chinese
| WPRIM
| ID: wpr-563673
ABSTRACT
Objective To observe the expression of Vascular endothelial growth factor 165 (VEGF165) in transplantation of MSCs to repair an ischemically damaged bind limb in a rabbit model.Methods MSCs were cultivated in vitro and transfected with non-replicative adenoviral vector with VEGF165 gene. Four weeks after treatment, Real-time PCR assessed the expression of VEGF165 in the damaged limb.Results It was confirmed that VEGF165 was successfully transfected into MSCs.Real-time PCR assessments revealed the expression of Vascular endothelial growth factor 165 (VEGF165) in 4 weeks after treatment. Conclusion VEGF165 can be transfected into MSCs and express in rabbit model of ischemic limb.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
Journal of Medical Research
Year:
2006
Type:
Article
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