Image quality evaluation of 64-slice spiral CT angiography in diagnosis of coronary artery disease / 第三军医大学学报

ABSTRACT

Objective To assessed the image quality and diagnostic value of the coronary artery diseases with 64-slice spiral computed tomography (64-SCT) angiography. Methods A retrospective image analysis of 39 patients who were diagnosed with coronary heart disease by both the 64-SCT and the invasive coronary angiography (CAG). Results In 507 coronary artery segments (13 coronary segments for each patient),1-,2-,3-class image quality by 64-SCT were in 185 (36.5%),236 (46.5%),86 (16.9%) segments respectively,and the heart rate range was respectively 62?5,66?4 and 75?10 per minute. Totally 421/507 (83.1%) segments that were of 1-,2-class image quality,met the requirements of clinical diagnosis,whereas 86/507 (16.9%) segments could not be sufficiently evaluated because of severe calcifications (51/86,59.3%) and/or motion artifacts (35/86,40.7%). Taking CAG as the gold standard diagnostic technique for coronary heart disease,of the lesions≥50% stenosis by 64-SCT (without any exclusion criteria),the overall sensitivity,specificity,accuracy,positive predictive value,and negative predictive value were 89.8%,94.9%,93.3%,88.5%,95.5%,respectively. Conclusion Our results indicate high diagnostic accuracy of coronary artery disease by 64-SCT compared to CAG. 64-SCT is a simple,convenient,safe and reliable,non-invasive effective method for diagnosis of coronary heart disease.