Experimental Study of the XML Injection Antagonizing Rat Pulmonany Hypertension by Monocrotaline / 医学研究杂志

ABSTRACT

Objective To observe the effect of xinmailong(XML) injection on rat pulmonary hypertension(PH) by monocrotaline(MCT).Methods SD rats were given a single intraperitoneal injection of MCT with 60mg/kg to induce the mold of PH. Three weeks later,these rats were treated with XML for 8d,and then PH was measured using Sun Puo’s method.Results PH and right ventricle hypertrophy model had been set up successfully by MCT.The ratio of wet weight(wW) and dry weight(dW) of the lung increased with P