Effects of the Velvet Antler Polypeptides on Spinal Nerve Cell Apoptosis Induced by ?-amyloid Peptide / 浙江中医药大学学报
Journal of Zhejiang Chinese Medical University
;
(6)2007.
Article
in Chinese
| WPRIM
| ID: wpr-564878
ABSTRACT
[Objective] To study effects of the velvet antler polypeptides on spinal nerve cell apoptosis induced by ?-amyloid peptide. [Method]Spinal nerve cells were performed serial subcultivation,and entered into experiment during the exponential phase of growth.The viability of spinal nervecells 24h after induction by ?-amyloid peptide with different concentrations were detected by MTT assay,percentages of the cell apoptosis and expression of casepase-3 were detected after induction by 25?mol/L ?-amyloid peptide.[Result]It was revealed that 24 h after treatment with ?-amyloid peptide of different concentrations,the viability of spinal nerve cells was significantly decreased in a dose-dependent manner(P
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Zhejiang Chinese Medical University
Year:
2007
Type:
Article
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