A systematic review of eradicating helicobacter pylori with ranitidine bismuth citrate / 中国实用内科杂志
Chinese Journal of Practical Internal Medicine
;
(12)2001.
Article
in Chinese
| WPRIM
| ID: wpr-564950
ABSTRACT
Objective To systematically review the Helicobacter pylori eradication efficacy with ranitidine bismuth citrate(RBC) and two antibiotics,and to conduct a meta-analysis of randomized clinical trials comparing the efficacy of proton pump inhibitor(PPI)vs RBC with two antibiotics for 1 week.Methods Selection of studiesstudies evaluating RBC plus two antibiotics were considered.For the meta-analysis,randomized controlled trials comparing PPI vs.RBC plus two antibiotics for 1 week were included.Data SourceRCTs were identified from CBM,handsearching,and personal contact with pharmaceutical companies.Inclusion criteriadata were extracted independently by two reviewers.The methodological quality of trials was assessed by the Jadad-scale.Statistics analysis was managed by using RevMan 4.2.Results Twelve randomized clinical trials including 1254 patients were included.The meta-analysis showed comparable efficacy with RBC and PPI (OR=1.30,95% CI0.94~1.81,P=0.12).Conclusion The efficacy of RBC and PPI-based triple regimens were comparable.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Controlled clinical trial
/
Prognostic study
/
Systematic reviews
Language:
Chinese
Journal:
Chinese Journal of Practical Internal Medicine
Year:
2001
Type:
Article
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