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Effect of Naoshuning on MMP-2/9 protein expression in traumatic brain injury rats / 中华中医药杂志
China Journal of Traditional Chinese Medicine and Pharmacy ; (12)2005.
Article in Chinese | WPRIM | ID: wpr-564995
ABSTRACT

Objective:

To explore the effect of Naoshuning on the protein expression of Matrix metalloproteinases(MMPs) in experimental injuried brain tissue of rats.

Methods:

Immunohistochemistry was used to determine the changes of protein expression of MMPs. Brain tissue water content,permeability and ultramicrostructure of blood-brain barrier(BBB) were also observed.

Results:

Compared with the sham group,the brain tissue water and EB content of injured side and the level of MMP-2 and MMP-9 protein expression in brain tissue around contusion in model group increased obviously(all P

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: China Journal of Traditional Chinese Medicine and Pharmacy Year: 2005 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: China Journal of Traditional Chinese Medicine and Pharmacy Year: 2005 Type: Article