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Transplantation of adipose derived mesenchymal stem cells for acute thoracolumbar disc disease with no deep pain perception in dogs
Journal of Veterinary Science ; : 123-126, 2016.
Article in English | WPRIM | ID: wpr-56502
ABSTRACT
Thirty-four dogs with no deep pain perception due to acute thoracolumbar intervertebral disc disease underwent decompression surgery within 1 week of diagnosis. All dogs underwent hemilaminectomy. Adipose derived mesenchymal stem cells (AD-MSCs) were transplanted into the injured spinal cord parenchyma for the AD-MSCs transplant dogs. Long-term outcome was evaluated at the end of the follow-up period (> 6 months). AD-MSCs combination treatment showed better recovery outcomes compared to decompression surgery alone. These results indicate that this stem cell therapy is a potential therapeutic strategy to overcome the limitations of treatment for spinal cord injury in clinical medicine.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Adipose Tissue / Acute Disease / Treatment Outcome / Decompression, Surgical / Mesenchymal Stem Cell Transplantation / Dog Diseases / Intervertebral Disc Degeneration / Pain Perception / Intervertebral Disc Displacement Limits: Animals Language: English Journal: Journal of Veterinary Science Year: 2016 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Adipose Tissue / Acute Disease / Treatment Outcome / Decompression, Surgical / Mesenchymal Stem Cell Transplantation / Dog Diseases / Intervertebral Disc Degeneration / Pain Perception / Intervertebral Disc Displacement Limits: Animals Language: English Journal: Journal of Veterinary Science Year: 2016 Type: Article