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Effects of glutamine on immune function of patients with severe craniocerebral trauma / 肠外与肠内营养
Parenteral & Enteral Nutrition ; (6)1997.
Article in Chinese | WPRIM | ID: wpr-565198
ABSTRACT

Objective:

To evaluate the effects of nutrition supplemented with glutamine on immune function and systemic inflammatory response in patients with severe craniocerebral trauma.

Methods:

Forty postoperative patients with severe craniocerebral trauma were randomized into experiment group(n=20) and control group(n=20).All patients received similar nitrogen and calorie for one week.Patients in experiment group were additionally supplemented with glutamine at dose of 0.50 g/(kg?d).Blood samples were obtained for measurement of IgM,IgG,IgA,CD3,CD4,CD8,CD4/CD8 before and after nutrition support the systemic inflammatory response syndrome(SIRS)was observed daily,and the serum albumin,transferin,hemoglobin and GCS were detected before and after nutrition support.

Results:

IgG,IgA,CD4,CD4/CD8,GCS and transferin in experiment group increased significantly after nutrition than in control group.

Conclusion:

Nutrition supplemented with glutamine may improve immune function,GCS and transferin in patients with severe cranial trauma.

Full text: Available Index: WPRIM (Western Pacific) Type of study: Controlled clinical trial Language: Chinese Journal: Parenteral & Enteral Nutrition Year: 1997 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Type of study: Controlled clinical trial Language: Chinese Journal: Parenteral & Enteral Nutrition Year: 1997 Type: Article