The effects of alanyl-glutamine dipeptide-enriched parenteral nutrition on outcome in radiation enteritis rats / 肠外与肠内营养
Parenteral & Enteral Nutrition
;
(6)1997.
Article
in Chinese
| WPRIM
| ID: wpr-565200
ABSTRACT
Objective:
To investigate the impact of alanyl-glutamine(Ala-Gln) on outcome in radiation enteritis rats.Methods:
Male SD rats(n=70)were separated randomly into four groups control group(n=10),AR+pseudosurgery group(n=20),AR+TPN group(n=20) and AR+TPN+Ala-Gln group(n=20).Rats were observed for mortality,changs of body weight,villous hight and area,the bcteriral translocation(BT)in mesenteric lymph nodes(MLNs),liver,spleen and peritoneal cavity.Serum TNF-? and sIL-2R level were determined by sandwich ELISA.Results:
When Ala-Gln was administered in radiation enteritis rat,the mortality,body weight loss and bacterial translocation were decreaded,the villous hight and area was increased and the TNF-? and sIL-2R levels were reduced.Conclusion:
Parenteral Ala-Gln nutrition can improves the results of radiation enteritis rats.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Parenteral & Enteral Nutrition
Year:
1997
Type:
Article
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