Effects of Trifoliumpratense Leguminosae extract on mouse allogenetic skin transplantation / 中华中医药杂志
China Journal of Traditional Chinese Medicine and Pharmacy
;
(12)2005.
Article
in Chinese
| WPRIM
| ID: wpr-565340
ABSTRACT
Objective:
To observe the effect of Trifoliumpratense Leguminosae extract (TLE) on mouse allogenetic skin transplantation.Methods:
Recipient BALB/c was divided into physiologic saline (PS) group and TLE group, full-thickness skins were transplanted through back to back method from donor C57BL/6. The allogenetic transplanted skin growth condition was observed. The proliferation of lymphocytes of recipient mice in vitro were detected by CFDA-SE stain and mixed lymphocyte reaction respectively.Results:
The allogenetic transplanted skin injected with TLE 25g/kg per day by vena caudalis growed better than that in PS group. The proliferation of lymphocyte in TLE group was smaller than that in PS group.Conclusion:
TLE maybe participate in the regulation of mouse immune system and induce its tolerance to the allogenetic transplanted skin.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Journal of Traditional Chinese Medicine and Pharmacy
Year:
2005
Type:
Article
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