ANALYSIS OF THE RELATIONSHIP BETWEEN LIPOPROTEIN LIPASE GENE POLYMORPHISM AND BLOOD FAT TRAITS / 营养学报
Acta Nutrimenta Sinica
;
(6)1956.
Article
in Chinese
| WPRIM
| ID: wpr-565487
ABSTRACT
Objective To investigate the effect of diet and gene on blood-fat trait of the individual.Method One hundred and twenty mice were fed with high fat emulsion for 4 w,then the genotypes of LPL were analyzed by PCR-SSCP to investigate their effect on blood-fat traits and some organ performance of mice.Result After fed with high fat emulsion for 4 w,98 mice suffered from hyperlipidemia,while 22 mice did not.And a G/A mutation was found in 220 targeted fragments we amplified at 14355 site,and association analysis showed that the mice with BB genotype had higher TC、TG、LDL、H/W、L/W level than those of the mice with AA genotype(P
Full text:
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Acta Nutrimenta Sinica
Year:
1956
Type:
Article
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