Polycythaemia vera in JAK2 Era / 中国实用内科杂志

ABSTRACT

The discovery of an acquired mutation affecting the gene for janus kinase 2(JAK2 V617F)in a high proportion of patients with polycythaemia vera(PV)represents a major breakthrough in molecular understanding of the PV.This article will review the impact of the JAK2 mutation on the diagnosis and treatment of PV.