Pharmacoepigenetics and interindividual variations in drug response / 中国药理学通报
Chinese Pharmacological Bulletin
;
(12)2003.
Article
in Chinese
| WPRIM
| ID: wpr-566145
ABSTRACT
With the development of pharmacogenetics and pharmacogenomics,pharmacoepigenetics potentially offers another level of explanation for interindividual variations in drug response that cannot be accounted for on the basis of genetic polymorphisms.Many genes encoding enzymes,drug transporters,transcription factors,drug targets,and nuclear receptors are under epigenetic control,which has implications in the context of interindividual variations in drug response as well as drug resistance during cancer treatment.In this overview,we summarize the newest advancement in this field.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Pharmacological Bulletin
Year:
2003
Type:
Article
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