Effect of Lactobacillus Plantarum on expression of tight-junctional molecules in rat hepatocytes during common bile duct ligation / 肠外与肠内营养
Parenteral & Enteral Nutrition
;
(6)2004.
Article
in Chinese
| WPRIM
| ID: wpr-566249
ABSTRACT
Objective:
To investigate the effects of oral Lactobacillus Plantarum supplementation on apoptosis of liver and tight junction of hepatocytes in an experimental model of obstructive jaundice.Methods:
Wistar rats were randomly divided into five groups sham-operated;bile duct ligation;bile duct ligation +LP(0.2 g/5 mL/day);bile internal drainage;bile internal drainage+LP.Hepatocyte apoptosis was quantitated using TUNEL assay.Transmission electron microscopy,RT-PCR and Western blot were used to observe tight junction associated proteins.Results:
Compared to the sham-operated,a significant increase in apoptosis(P
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Parenteral & Enteral Nutrition
Year:
2004
Type:
Article
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