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Establishment of Age- and Gender-Specific Reference Ranges for 36 Routine and 57 Cell Population Data Items in a New Automated Blood Cell Analyzer, Sysmex XN-2000
Annals of Laboratory Medicine ; : 244-249, 2016.
Article in English | WPRIM | ID: wpr-56702
ABSTRACT
We established age- and gender-specific reference ranges for the 36 routine complete blood cell (CBC) and 57 cell population data (CPD) items in the Sysmex XN-2000 (Sysmex, Japan). In total, 280 peripheral blood samples were obtained from an equal number of healthy adults. Values for 36 routine items and 57 CPD items were obtained for each sample, and the results were categorized into six subgroups (N>39 in each subgroup) according to patient age (20-40, 41-60, and >60 yr) and gender (male and female), and compared with respect to age and gender differences. The majority of data items (22 of 36 routine CBC items and 44 of 57 CPD items) exhibited significant differences (P< or =0.05) in their results with respect to age or gender, and several red cell-, lymphocyte-, and platelet-related data tended to decrease in women or older adults. These results provide a basis for establishing age- and gender-specific reference ranges for routine and CPD items in Sysmex XN-2000. Furthermore, these reference ranges could be used to determine clinical significance for new items of Sysmex XN-2000 in further studies.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Reference Values / Automation / Blood Cell Count / Sex Factors / Age Factors Limits: Adult / Aged / Female / Humans / Male Language: English Journal: Annals of Laboratory Medicine Year: 2016 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Reference Values / Automation / Blood Cell Count / Sex Factors / Age Factors Limits: Adult / Aged / Female / Humans / Male Language: English Journal: Annals of Laboratory Medicine Year: 2016 Type: Article