Effect of Qingxin Yangshen Chinese herbs on ?-adrenoceptor in cardiocytes of stress rats / 中华中医药杂志
China Journal of Traditional Chinese Medicine and Pharmacy
;
(12)2005.
Article
in Chinese
| WPRIM
| ID: wpr-567506
ABSTRACT
Objective:
To investigate the effects of Qingxin Yangshen Chinese herbs on ?-adrenoceptor in cardiocytes of stress rats.Methods:
Adopting the method of radoligand binding,the affinity of ?-adrenoceptor of experimental myocardium cells and density were analyzed.Meanwhile,RT-PCR was used to test mRNA of ?-adrenoceptor of myocardium cells.To observe the effect of Qingxin Yangshen Fang on ?-adrenoceptor of myocardium cells of stress rats,and the Zhusha Anshen Pills and Propranololas the control groups.Results:
All the three groups above can increase the affinity of ?-adrenoceptor of experimental myocardium cells,promote its sensitivity and notably inhibit the decrease of density of receptors and control down-regulation of expression of ?1-ARmRNA induced by stress,and regulate up the expression of ?2-ARmRNA.Conclusion:
The Chinese herbs of Qingxin Yangshen had the effect of acceptor inhibiting and can regulate the changes of ?-adrenoceptor of myocardium cells induced by stress.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Journal of Traditional Chinese Medicine and Pharmacy
Year:
2005
Type:
Article
Similar
MEDLINE
...
LILACS
LIS