Effect of Combined Acupuncture and Medicine on Learning-Memory Ability and Free Radical System of Hippocampus in Vascular Dementia Rats / 浙江中医药大学学报
Journal of Zhejiang Chinese Medical University
;
(6)2006.
Article
in Chinese
| WPRIM
| ID: wpr-567602
ABSTRACT
[Objective]To explore the effect of combined acupuncture and medicine on learning--memory abilities,and free radical system of hippocampus in vascular dementia(VD)rats.[Methods]The 48 Sprague Dawley rats were randomly divided into control(1),VD model(2),VD plus removed olfactory bulb model(3)and XIU Three Needles(4),Eugenol(5),combined acupuncture and medicine(6)groups.Morris maze tests were conducted for valuating the learning and memory abilities.The contents of MDA,SOD and GSH-Px activity of hippocampus were detected.[Results]In comparison with group 1,the average escape latency and travel distance prolonged significantly in group 2.In comparison with group 2,it shortened remarkably in groups 4 and 5.No significant differences were found between groups 1 and 2.In comparison with group 6,it prolonged in groups 4 and 5.No significant differences were found between them.The MDA content of hippocampus in VD model group was higher than that of control group(P
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Zhejiang Chinese Medical University
Year:
2006
Type:
Article
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