Impact of saiga horn capsule on blood pressure variability,pulse pressure and left ventricular mass in elderly patients with isolated systolic hypertension / 中华中医药杂志

ABSTRACT

Objective:To observe the efficacy of saiga horn capsule combining with benazapril on blood pressure variability,pulse pressure and left ventricular mass in elderly patients with isolated systolic hypertension (ISH).Methods:78 elderly patients with ISH were treated with saiga horn capsule combining with benazapril for 4 months.We compared the change of 24hours systolic blood pressure (SBP),24hours diastolic blood pressure (DBP),pulse pressure (PP) and left ventricular mass.Results:After four months treatment,reduction of 24 hour SBP variability,day SBP variability,DBP variability,night SBP variability day,24 hour and day average BP variability,pulse pressure and left ventricular mass had statistical signifi cance (P0.05).Conclusion:The elderly patients with ISH treated with saiga horn capsule and benazapril can lower blood pressure,pulse pressure more effective,therefore protect target organ better than with benazapril only.