Study on effect of ultramicro-shatter technology on penetrating skin absorption of Pollen Typhae in Zhongtongxiao Cataplasm / 中华中医药杂志
China Journal of Traditional Chinese Medicine and Pharmacy
;
(12)2006.
Article
in Chinese
| WPRIM
| ID: wpr-568186
ABSTRACT
Objective:
To study the effect of ultramicro-shatter technology on penetrating skin absorption of isorhamnetin-3-O-neohesperidin in Zhongtongxiao Cataplasm.Methods:
To apply reformed Frans penetrating skin absorption cell marching extraorgan penetrating skin experiment.HPLC method was used to determine the content of isorhamnetin-3-Oneohesperidin in ultramicro-shatter Zhongtongxiao Cataplasm and in common Zhongtongxiao Cataplasm.Results:
The Q-t equation of ultramicro-shatter Zhongtongxiao CataplasmQ=3.0382t+47.082,penetrating skin velocity3.0382(?g.cm2/h);the Q-t equation of common Zhongtongxiao CataplasmQ=2.7967t+39.752,penetrating skin velocity2.7967(?g.cm2/h);Extraction rate of dynamic extracting micro-powder,the ephedrina hydrochloridum,glycyrrhizic acid and glycyrrhizae glycoside were higher than the trdtional cut crude drug decocting.Conclusion:
The accumulating osmolality and penetrating skin velocity of isorhamnetin-3-O-neohesperidin in ultramicro-shatter Zhongtongxiao Cataplasm were all better than those in common Zhongtongxiao Cataplasm,it explained that ultramicro-shatter technology accelerate the dissolution of medicine compsitions.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Journal of Traditional Chinese Medicine and Pharmacy
Year:
2006
Type:
Article
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