THE LOCALIZATION OF VIRUS ANTIGEN OF EPIDEMIC HEMORRHAGIC FEVER IN INFECTED SUCKLING MICE BRAIN---A STUDY WITH INDIRECT IMMUNOFLUORESCENCE TECHNIQUE / 解剖学报

ABSTRACT

The distribution of virus antigen of epidemic hemorrhagic fever (EHF) in infected suckling mice brain was studied by indirect immunofluorescence procedure. The specific fluorescence was presented in the following areas (l)the limbic system, including the cingulate cortex, the piriform cortex, the anterior olfactory nucleus, the lateral septal nucleus, the hippocampus, the dental gyrus, the dorsomedial nucleus and lateral nuclei of thalamus, and several nuclei of the hypothalamus; (2)the special sensory nuclei, such as the medial and spinal vestibular nuclei, the cochlear nucleus, and the lateral lemniscus nucleus; (3)the nuclei associated with analgesic function, including the periaqueductal gray substance, the trigeminal sensory nucleus, the raphe nuclei of midbrain etc; (4)the extrapyramidal structures, for example, the caudal-putamen, the pallidum, the entopeduncular nucleus, the cerebellum and several nuclei of reticular formation in brainstem.