HISTOGENESIS OF THE HUMAN RETINA / 解剖学报

ABSTRACT

62 cases of human fetal and 2 neonatal retina specimens were observed with LM. The thickness of the outer pigmented epithelium was reduced and changed from pseudostratified columnar to a simple cuboid layer at 8-9 weeks. The initial differentiation of neuro-epithelium was divided into an outer and an inner neuroblastie layers, between them was a transient layer of Chievitz which disappeared at 10-11 weeks. At the same time the differentiating ganglion cells were migrated from the inner neuroblast layer toward the marginal layer. The developing ganglion cell layer, inner plexiform layer and nerve fiber layer could be identified until 12-13 weeks. During 11-14 weeks, the precusors of cones were occurred at the outermost row of outer neuroblast layer, and the developing rods, outer plexiform layer and inner nuclear layer were recognizable during 15-20 weeks. Differentiation of the peripheral retina was later than the central portion during the fetal period. Histogenesis; Retina; Optic disc; Human fetus