RESEARCH INTO PHARMACODYNAMICS OF BIFONAZOLE / 重庆医科大学学报

ABSTRACT

Bifonazole is a new imidazolyl derivative, with broad spectrum anlimycotic activity. In our experiment, 100 strains of common dermatophytes in clinical practice were used to evaluate the MIC of Bifonazole. All the species tested, were sensitive to this agent, and the MIC values of 79% of strains were under 4g/ml. The MIC value was influenced by inoculum size, the larger the inoculum size, the larger the MIC value. It was found that the efficacy of Bifonazole is comparable to Mico-nazole