A STUDY ON QUANTITATIVE ALTERATION OF 5srRNA DURING THE DEVELOPMENT OF MAMMALIAN ERYTHROCYTES / 解剖学报
Acta Anatomica Sinica
;
(6)1954.
Article
in Chinese
| WPRIM
| ID: wpr-569114
ABSTRACT
The present study reported that 5srRNA from reticulocytes of rabbit could pass into the nucleus of mouse myeloma cells SP2/0,and in the mean time DNA synthesis and cells division were markedly suppressed. In a separate experiment, the rRNA was extracted from embryonic liver and erythrocytes of rabbit or rat and analysed by agarose electrophoresis method. The result indicated that the amount of 5srRNA in various period of the development of erythrocyte is changed along with denucleation process. Thus it is likely that 5srRNA of mammalian erythrocyte plays a role in reversing malignant phenotype of tumor cells and promoting denucleation of mammalian erythrocyte through inhibiting DNA synthesis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Acta Anatomica Sinica
Year:
1954
Type:
Article
Similar
MEDLINE
...
LILACS
LIS