The Effects of Zhigancao and Glycyrrhizic Acid on Transmural Potential of Reverted Mouse Small Intestine in Vitro / 中草药
Chinese Traditional and Herbal Drugs
;
(24)1994.
Article
in Chinese
| WPRIM
| ID: wpr-569479
ABSTRACT
Electrical potential difference (PD) was measured across the wall of reverted small intestinal saes of mice. The effect of glycyrrhizic acid on transmural potential related to Na+ and glucose transport were investigated. It was found that both zhigancao (100g/L ) and glycyrrhizic acid (2. 5mmol/L ) decreased the PD (P<0.01).According to the theory of active transport of glucose, we inferred that zhigancao and glycyrrhizic acid possibly produce an inhibitiory effect on Na+. K+-ATP ase,resulted in a blocking effect on sodium channel.
Full text:
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Traditional and Herbal Drugs
Year:
1994
Type:
Article
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