Effects of Tangut Dragonhead (Dracocephalum tanguticum)on Blood Rheology and Tissuse Morphology in Rats / 中草药

ABSTRACT

The effects of an aqueous extract of Dracocephalum tanguticum Maxim. (DtM ) on p, b.b-1/ H. Hct. ESR. ESR-kand EPT of rats were studied by ip route. The animals were divided into three groups normal pressure control group (NCG ). iowpressure treatment group (LTG )and lowpressure control group (LCG ). A11 p,b. Het. ESR-k increased stignificantly in rats exposed to stimulated altitude of 6500m for 10 days (8h/day),and the platelet and the ratio of left to ri1ght ventricle weights were obviously decreased in comparison with NPG. The above parameters of LTG .except Het.have noobvious difference as compared with NCG, Het in LTG increased obviously but lower than LCG. These results suggested that DtM may be used as an inhibitory agent against the changes of induced-hypoxia blood rheology, decreased platelet and hypertrophic right ventricle. In addition,the observation of tissue morphology showed that DtM possesses sometherapeutic effects to injuries of lung. liver and kidney of hypoxia rats.