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A Preliminary Study on the Establishment of Animal Model with Hyperuricemia / 中药新药与临床药理
Traditional Chinese Drug Research & Clinical Pharmacology ; (6)2000.
Article in Chinese | WPRIM | ID: wpr-569634
ABSTRACT
Hypoxanthine,the pre_substance of uric acid,was used to create mouse model with hyperuricemia.The dose_effect relationship and time_effect relationship of hypoxanthine during the model establishment were observed.The effect of sex and xanthine oxidase inhibitor on the establishment of mouse model was studied.The results showed this method is effective for the establishment of a stable mouse model with hyperuricemia.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Traditional Chinese Drug Research & Clinical Pharmacology Year: 2000 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Traditional Chinese Drug Research & Clinical Pharmacology Year: 2000 Type: Article