Clinical Study on Relationship Between Blood Stasis Syndrome and Platelet Adhesion Molecules / 广州中医药大学学报

ABSTRACT

Objective To explore the relationship between Qi_stagnation with blood stasi s, Qi_deficiency with blood stasis and platelet activation. Methods Expressi on levels of lysosomal integral membrane protein (CD?63), alpha_granu le membrane protein (CD?62?p) and thrombospondin (TSP)were the specific index es of platelet activation. Te chnique of monoclonal antibody analysis and flow cytometry were used to detect the expression levels of CD?63, CD?62?p and TSP. Fifty_eight cases of Qi_st agnation with blood stasis syndrome were allocated to Group A and 60 cases of Qi _deficiency with blood stasis syndrome to Group B, and 30 healthy volunteers ser ved as the control (Group C). Results Expression levels of CD63, CD62p an d TSP were higher in Group A than in Group B and Group C (P