Effect of thalidomide on the expression of VEGF mRNA in human breast cancer cell lines / 中国基层医药
Chinese Journal of Primary Medicine and Pharmacy
;
(12): 1057-1058,倒插1, 2008.
Article
in Chinese
| WPRIM
| ID: wpr-569980
ABSTRACT
Objective To assess the effects of thalidomide on VEGF mRNA level in human breast cancer cell lines. Methods Breast cancer cells were treated with thalidomide for 24~72h, RT-PCR was uced to detect the level of VEGF mRNA expression. Results When the concentration of drug is 50μg/L,thalidomide strongly inhibited the level of VEGF mRNA expression. Conclusion Within certain concentration range of thalidomide can inhibit the level of VEGF mRNA expression in breast cancer cell.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Primary Medicine and Pharmacy
Year:
2008
Type:
Article
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